The starting point for the synthesis and application of coordination complexes in science and technology is very often nickel as the center of the coordination complex. Nanosynthesized, structurally diverse nickel complexes, oxides and hydroxides are widely used today due to their structural properties. Due to its exceptional properties, nickel is often used as the central atom/ion, or coordination center, in the synthesis of coordination complexes. The aim of this work is to review the literature, synthesize a Ni complex and investigate its possible application for sensory or catalytic purposes. The active coordination center for possible application is Ni(II)/Ni(III). Hydrothermal synthesis and characterization of the coordination complex of nickel(II) with 6-hydroxynicotinic acid and 4,4'-bipyridine as ligands was carried out. The prepared complex are characterized by infrared spectroscopy with Fourier transformation, scanning electron microscopy and electrochemical methods. The electrochemical characterization aimed to study the stability of the complex and to investigate the methanol oxidation reaction on the surface of the electrode modified with the Ni(II) complex. Based on the IR spectrum and solved structures of 1D polymers, the structural and empirical formula of the complex was derived - {[C 10 H 16 NiN 2 O 4 ](C 6 H 4 NO 3 ) 2 ×2H 2 O} n or {[Ni(4,4'-bpy)(H 2 O) 4 ](6-onic) 2 ×2H 2 O} n . The creation of metal ions with high oxidation state (Ni 2+ ↔ Ni 3+ ) and the understanding of electron transfer reaction are the key to understand and improve the electrooxidation of methanol. The research results showed that the electrode modified with the Ni complex exhibited excellent catalytic activity toward methanol and linear response with respect to concentration, offering great potential for the development of sensors based on this complex. The good stability of the obtained complex in a wide range of potentials indicates a possible much broader application in the sensor industry.