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master's thesis
Artemisia absinthium L.: Kemijski sastav i biološka aktivnost
diplomski rad
2021. urn:nbn:hr:167:258347
Šimić, Anja
University of Split
Faculty of Chemistry and Technology
Division of Chemistry

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Šimić, A. (2021). Artemisia absinthium L.: Kemijski sastav i biološka aktivnost : diplomski rad (Master's thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:258347

Šimić, Anja. "Artemisia absinthium L.: Kemijski sastav i biološka aktivnost : diplomski rad." Master's thesis, University of Split, Faculty of Chemistry and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:167:258347

Šimić, Anja. "Artemisia absinthium L.: Kemijski sastav i biološka aktivnost : diplomski rad." Master's thesis, University of Split, Faculty of Chemistry and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:167:258347

Šimić, A. (2021). 'Artemisia absinthium L.: Kemijski sastav i biološka aktivnost : diplomski rad', Master's thesis, University of Split, Faculty of Chemistry and Technology, accessed 23 April 2024, https://urn.nsk.hr/urn:nbn:hr:167:258347

Šimić A. Artemisia absinthium L.: Kemijski sastav i biološka aktivnost : diplomski rad [Master's thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2021 [cited 2024 April 23] Available at: https://urn.nsk.hr/urn:nbn:hr:167:258347

A. Šimić, "Artemisia absinthium L.: Kemijski sastav i biološka aktivnost : diplomski rad", Master's thesis, University of Split, Faculty of Chemistry and Technology, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:167:258347

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Metadata
TitleArtemisia absinthium L.: Kemijski sastav i biološka aktivnost : diplomski rad
Title (english)Artemisia absinthium L.: Chemical composition and biological activity : diploma thesis
AuthorAnja Šimić
MentorOlivera Politeo (mentor)
Committee memberMario Nikola Mužek (predsjednik povjerenstva)
Committee memberLea Kukoč Modun (član povjerenstva)
Committee memberOlivera Politeo (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Chemistry)
Split
Defense date and country2021-10-19, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Cilj ovog rada bio je izolirati i odrediti kemijski sastav eteričnih ulja pelina (Artemisia absinthium L.) sakupljenih na različitim lokalitetima te u različitim sezonama, ispitati sposobnost inhibicije eteričnih ulja na djelovanje enzima acetilkolinesteraze, butirilkolinesteraze i α-glukozidaze te istražiti antioksidacijsku aktivnost. Predominantni spojevi eteričnog ulja pelina iz Sinja su cis-sabinil-acetat i cis-epoksi-ocimen, eteričnog ulja pelina iz Mostara su cis-epoksi-ocimen i cis-krizantemil-acetat, eteričnog ulja pelina iz Zaboka su trans-tujon i cis- epoksi-ocimen te ulja pelina iz Obrovca je cis-epoksi-ocimen. Kod svih analiziranih uzoraka ulja ove biljke sabrane na različitim lokacijama i u različitim sezonama branja kao dominantne komponente ulja javljaju se oksidirani monoterpenski spojevi-monoterpenoidi. Eterična ulja biljke A. absinthium L. pokazuju umjerenu ili slabu sposobnost inhibicije enzima AChE i BChE, ne inhibiraju ili umjereno inhibiraju enzim α-glukozidazu, pokazuju slab redukcijski potencijal i ne pokazuju sposobnost hvatanja slobodnih DPPH radikala.
Abstract (english)
The aim of this study was to isolate and determine the chemical composition of essential oils of wormwood (Artemisia absinthium L.) collected at different sites and in different seasons, to examine the ability to inhibit essential oils on the enzymes acetylcholinesterase, butyrylcholinesterase and α-glucosidase and to investigate antioxidant activity. The predominant compounds of wormwood essential oil from Sinj are cis-sabinyl-acetate and cis-epoxy-ocimen, wormwood essential oil from Mostar are cis-epoxy-ocimen and cis-chrysanthemum-acetate, wormwood essential oil from Zabok are trans-thujone and cis-epoxy-ocimen and oils wormwood from Obrovac is cis-epoxy-ocimen. In all analyzed oil samples of this plant collected at different locations and in different harvesting seasons, oxidized monoterpene compounds-monoterpenoids appear as the dominant oil components. The essential oils of A. absinthium L. show moderate or weak ability to inhibit the enzymes AChE and BChE, do not inhibit or moderately inhibit the enzyme α-glucosidase, show weak reduction potential and do not show the ability to capture free DPPH radicals.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:258347
Study programmeTitle: Chemistry; specializations in: Environmental Protection, Organic Chemistry and Biochemistry
Course: Environmental Protection
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2024-01-17
Terms of useLicence In copyright icon
Created on2022-01-17 09:11:09