Honey is a natural sweetener known through the world. In addition to being a natural sweetener, since ancient times, honey has been recognized as a healing agent. Ever since, honey is not only used as nutrition, but also used for different indications. Phytochemicals are derived from plants from which bees collect nectar or a delicious honey dew, and it has been proved that many of them can benefit the health. Antioxidants present in the honey can be enzymatic (catalase, glucose oxidase) and non-enzymatic (organic acids, products of Maillard reactions, amino acids, proteins, flavonoids, phenols, vitamin E, vitamin C, carotenoids ). Flavonoids present in honey are usually pinocembrin, apigenin, kaempferol, quercetin, galangin, chrysin, pinobanksin, luteolin and hesperitin. Today, honey is used because it's antimicrobial activity, anti-inflammatory activity, as dressing to promote healing of wounds, burns and skin ulcers. Also, honey is used in gastroenterology as prebiotics, antibacterial agent and rehydrating agent for the treatment of childs gastroenteritis, antibacterial agent and healing-promoting agent for the treatment of dyspepsia and peptic ulcers. Honey is used in sports as a quick source of energy. In diabetics, honey has a positive impact on reducing complications. Honey has positive effects on cardiovascular health. Stomatitis and other oral lesions can be successfully treated with honey. Numerous reports from around the world detail the use of honey to treat ophthalmologic disorders. Honey is also use in oncology. It may be an effective cough suppressant. It is used because its anti-influenza viral effects, as topical antifungal agent for the treatment of tineas etc.