Sustainable solid waste management refers to a mode of waste management in accordance with urban development in which resource use aims to meet human needs of daily consumption while ensuring the sustainability of natural systems and the environment through appropriate waste management. However, the interactions between human activities and the environment are complicated and often difficult to quantify. The analytical tool LCA (Life-Cycle Assessment) can aid in the development of a sustainable solid municipal waste management practice and a comprehensive understanding of the waste management system. In this thesis, the environmental effects of the City of Zagreb's solid municipal waste management system were examined using a computer program IWM-EPIC/CSR (Integrated Waste Management-Environment and Plastics Industry Council and Corporations Supporting Recycling). Four municipal waste management scenarios were taken into consideration in accordance with the objectives of the Croatian waste legislation based on waste statistics for the City of Zagreb for the year 2020. After analyzing and comparing the environmental impacts of different scenarios of the waste management system, it was concluded that the implementation of the municipal waste management system, which is an improvement of the existing system and is aligned with the waste management hierarchy, would reduce all significant impacts on human health and would reduce environmental degradation and greatly reduce the extraction of irreversible natural resources.