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undergraduate thesis
Identifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom
završni rad
2022. urn:nbn:hr:167:914354
Mrvelj, Jure
University of Split
Faculty of Chemistry and Technology
Division of Chemistry

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Mrvelj, J. (2022). Identifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom : završni rad (Undergraduate thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:914354

Mrvelj, Jure. "Identifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2022. https://urn.nsk.hr/urn:nbn:hr:167:914354

Mrvelj, Jure. "Identifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2022. https://urn.nsk.hr/urn:nbn:hr:167:914354

Mrvelj, J. (2022). 'Identifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom : završni rad', Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, accessed 02 April 2024, https://urn.nsk.hr/urn:nbn:hr:167:914354

Mrvelj J. Identifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom : završni rad [Undergraduate thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2022 [cited 2024 April 02] Available at: https://urn.nsk.hr/urn:nbn:hr:167:914354

J. Mrvelj, "Identifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom : završni rad", Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, Split, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:167:914354

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Metadata
TitleIdentifikacija hlapljivih organskih metabolita u urinu trudnih žena s preeklampsijom : završni rad
Title (english)IDENTIFICATION OF VOLATILE ORGANIC METABOLITES IN URINE OF PREGNANT WOMAN WITH PREECLAMPSIA : bachelor thesis
AuthorJure Mrvelj
MentorMila Radan (mentor)
Committee memberMila Radan (predsjednik povjerenstva)
Committee memberMarija Bralić (član povjerenstva)
Committee memberMladen Miloš (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Chemistry)
Split
Defense date and country2022-07-14, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Različiti organizmi kao što su bakterije, plijesni i ljudi proizvode i oslobađaju relativno nepoznatu klasu metabolita. Ovi hlapljivi organski metaboliti skraćeno nazvani VOM (engl. Volatile organic metabolites) predstavljaju svojevrsni biosignal koji odražava zbroj svih utjecaja, uključujući genetiku, čimbenike okoliša, stanje prehrane i bolesti. Do sada su hlapljivi organski metaboliti kod ljudi otkriven u različitim tjelesnim medijima, kao na primjer u koži, u izdahnutom zraku, te u tjelesnim tekućinama kao što su slina, majčino mlijeko, znoj, krv i urin. Primjenom vezanog sustava plinske kromatografije i spektrometrije masa(GC-MS) uz prethodnu mikroekstrakciju na čvrstoj fazi određeni su hlapljivi metaboliti u uzorku urina trudnih žena s preeklampsijom. Za identifikaciju pojedinih metabolita korišteni su spektri masa i knjižnica spektara masa NIST. Od identificiranih metabolita naglasak je stavljen na one koji su povišeni kod oboljelih žena i potencijalni subiljezi za ovu bolest.
Abstract (english)
Various organisms such as bacteria, molds and humans produce and release a relatively unknown class of metabolites. These volatile organic metabolites, abbreviated as VOMs (Volatile organc metabolites), are a kind of biosignal that reflects the number of all influences, including genetics, environmental factors, diet and disease. To date, volatile organic metabolites in humans have been detected in various bodily media, such as skin, exhaled air, and body fluids such as saliva, breast milk, sweat, blood, and urine. Using a coupled system of gas chromatography and mass spectrometry(GC-MS) with prior solid phase microextraction, volatile metabolites were determined in a urine sample of pregnant women with preclampsia. The NIST mass spectrum library was used to identify individual metabolites. Of the identified metabolites, emphasis is placed on those that are elevated in affected women and are potential markers for this disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:914354
Study programmeTitle: Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2022-08-21
Terms of useLicence In copyright icon
Created on2022-07-21 07:42:57