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undergraduate thesis
Metaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji
završni rad
2021. urn:nbn:hr:167:263153
Živalj, Patricia
University of Split
Faculty of Chemistry and Technology
Division of Chemistry

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Živalj, P. (2021). Metaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji : završni rad (Undergraduate thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:263153

Živalj, Patricia. "Metaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:167:263153

Živalj, Patricia. "Metaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:167:263153

Živalj, P. (2021). 'Metaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji : završni rad', Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:167:263153

Živalj P. Metaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji : završni rad [Undergraduate thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2021 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:167:263153

P. Živalj, "Metaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji : završni rad", Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:167:263153

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Metadata
TitleMetaboličko profiliranje za detekciju bolesti temeljeno na masenoj spektrometriji : završni rad
Title (english)Mass spectrometry-based metabolic profiling for disease detection : bachelor thesis
AuthorPatricia Živalj
MentorMila Radan (mentor)
Committee memberMladen Miloš (predsjednik povjerenstva)
Committee memberTea Bilušić (član povjerenstva)
Committee memberMila Radan (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Chemistry)
Split
Defense date and country2021-09-28, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Masena spektrometrija igra važnu ulogu u pronalaženju biomarkera za detekciju bolesti. Visokokvalitetni kvantitativni podaci potrebni su za preciznu analizu metaboličkih smetnji kod pacijenata. Ovaj rad opisuje nedavne napretke u istraživanju metabolizma temeljenom na masenoj spektrometriji s primjenom u detekciji nekoliko najzastupljenijih ljudskih bolesti, s fokusom na istraživanje kohorta, korištene maseno spektrometrijske platforme, statističke analize i identifikaciju razlikovnih metabolita. Sumirani su potencijalni nedavno otkriveni biomarkeri za dijabetes tipa 2, kardiovaskularne bolesti, hepatocelularni karcinom te su raspravljena ograničenja i mogućnosti.
Abstract (english)
Mass spectrometry plays an important role in seeking biomarkers for disease detection. High-quality quantitative data is needed for accurate analysis of metabolic perturbations in patients. This thesis describes recent developments in mass spectrommetry-based metabolomics research with applications to the detection of several major common human diseases, focusing on study cohorts, mass spectrometry platforms utilized, statistical analyses and discriminant metabolite identification. Potential disease biomarkers recently discovered for type 2 diabetes, cardiovascular diseases,hepatocellular carcinoma are summarized and limitations and possibilities are discussed.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:263153
Study programmeTitle: Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-12-02 10:37:23