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master's thesis
Biološka aktivnost eteričnih ulja celera i đumbira
diplomski rad
2020. urn:nbn:hr:167:325608
Viduka, Karla
University of Split
Faculty of Chemistry and Technology
Division of Engineering and Chemistry

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Viduka, K. (2020). Biološka aktivnost eteričnih ulja celera i đumbira : diplomski rad (Master's thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:325608

Viduka, Karla. "Biološka aktivnost eteričnih ulja celera i đumbira : diplomski rad." Master's thesis, University of Split, Faculty of Chemistry and Technology, 2020. https://urn.nsk.hr/urn:nbn:hr:167:325608

Viduka, Karla. "Biološka aktivnost eteričnih ulja celera i đumbira : diplomski rad." Master's thesis, University of Split, Faculty of Chemistry and Technology, 2020. https://urn.nsk.hr/urn:nbn:hr:167:325608

Viduka, K. (2020). 'Biološka aktivnost eteričnih ulja celera i đumbira : diplomski rad', Master's thesis, University of Split, Faculty of Chemistry and Technology, accessed 18 April 2024, https://urn.nsk.hr/urn:nbn:hr:167:325608

Viduka K. Biološka aktivnost eteričnih ulja celera i đumbira : diplomski rad [Master's thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2020 [cited 2024 April 18] Available at: https://urn.nsk.hr/urn:nbn:hr:167:325608

K. Viduka, "Biološka aktivnost eteričnih ulja celera i đumbira : diplomski rad", Master's thesis, University of Split, Faculty of Chemistry and Technology, Split, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:167:325608

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Metadata
TitleBiološka aktivnost eteričnih ulja celera i đumbira : diplomski rad
Title (english)Biological activity of celery and ginger essential oil : graduate thesis
AuthorKarla Viduka
MentorFranko Burčul (mentor)
Committee memberDanijela Skroza (predsjednik povjerenstva)
Committee memberZvonimir Marijanović (član povjerenstva)
Committee memberFranko Burčul (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Engineering and Chemistry)
Split
Defense date and country2020-10-20, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Alzheimerova bolest je jedna od najčešćih degenerativnih bolesti mozga, a karakterizira ju oštećenje živčanih stanica i propadanje kognitivnih funkcija. Pravi lijek nije poznat, ali se najčešće primjenjuju inhibitori acetilkolinesteraze. U ovom radu kao potencijalni inhibitori ispitana su eterična ulja đumbira (Zingiber officinale Roscoe) i celera (Apium graveolens L.). Kako bi se utvrdila potencijalna inhibicijska sposobnost ispitivanih ulja korištena je modificirana spektrofotometrijska metoda po Ellmanu. Prema dobivenim rezultatima vidljivo je da eterično ulje đumbira nema inhibicijskih sposobnosti, dok eterično ulje celera pokazuje inhibicijsku aktivnost ovisno o koncentraciji ispitivane otopine. Ulja su također ispitivana i na antioksidacijsku aktivnost pomoću DPPH i FRAP metoda te se prema dobivenim rezultatima može zaključiti da ni jedno od ispitivanih ulja nema značajnu antioksidativne sposobnosti. Sastav eteričnih ulja određen je GC-MS analizom te su se kao najzastupljeniji spojevi u eteričnom ulju celera pokazali limonen, β-selinen, sedanenolid, 3-n-butilftalid, α-selinen, dok su kod eteričnog ulja đumbira to α-zingiberen, β-seskvifelandren, β-bisabolen te α-kurkumen.
Abstract (english)
Alzheimer's disease is one of the most common degenerative diseases of the brain, and it is characterized by damage to nerve cells and deterioration of cognitive functions. The exact drug is not known, but acetylcholinesterase inhibitors are most used. In this work, the essential oils of ginger (Zingiber officinale Roscoe) and celery (Apium graveolens L.) are tested as potential inhibitors. A modified Ellman spectrophotometric method was used to determine the potential inhibitory ability of the tested oils. According to the obtained results, it is evident that ginger essential oil has no inhibitory abilities, while celery essential oil shows inhibitory activity depending on the concentration of the test solution. The oils were also tested for antioxidant activity using DPPH and FRAP methods, and according to the obtained results, it can be concluded that none of the tested oils has significant antioxidant capacity. The composition of essential oils was determined by GC-MS analysis, and the most common compounds in celery essential oil were limonene, β-selinene, sedanenolide, 3-n-butylphthalide, α-selinene, while in ginger essential oil it was α-zingiberene, β-sesquifelandrene, β-bisabolene and α-curcumene.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:325608
ProjectNumber: IP-2014-09-6897
Title: Istraživanje bioaktivnih spojeva iz dalmatinskogbilja: njihov antioksidacijski karakter i utjecaj na enzimsku inhibiciju i zdravlje
Acronym: BioActCom
Leader: Mladen Miloš
Jurisdiction: Croatia
Funder: HRZZ
Funding stream: IP
Study programmeTitle: Food technology - graduate - university
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjerka prehrambene tehnologije (magistar/magistra inženjerka prehrambene tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-12-02 13:04:02